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Lipidemic effects of an interesterified mixture of butter, medium‐chain triacylglycerol and safflower oils
Author(s) -
Mascioli Edward A.,
McLennan Christine E.,
Schaefer Ernst J.,
Lichtenstein Alice H.,
Høy CarlErik,
Christensen Michael S.,
Bistrian Bruce R.
Publication year - 1999
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/s11745-999-0437-x
Subject(s) - interesterified fat , food science , lipidology , chemistry , clinical chemistry , edible oil , safflower oil , organic chemistry , lipase , biochemistry , enzyme
Abstract The objective of this study was to determine if the positional structure of dietary triacylglycerol affected lipidemic responses. Thirty healthy adults (16 men and 14 postmenopausal women) with low‐density lipoprotein cholesterol (LDL‐C) concentrations >3.37 mM (130 mg/dl) enrolled in a prospective, single‐blind, cross‐over outpatient clinical trial that consisted of two 5‐wk dietary phases. After baseline screening, subjects were instructed to follow individualized meal plans (weight maintenance diets with 36% of total energy from fat, half of which was from a test oil) and randomized to receive either butter (B) or an interesterified mixture (IM) of butter, medium‐chain triacylglycerol (MCI), and safflower oils. Blood drawn during weeks 5 and 10 of feeding was analyzed for total cholesterol (TC), high density lipoprotein cholesterol (HDL‐C), LDL‐C, and triacylglycerols (TAG). Mean plasma levels of TC (B, 6.98±1.06 mM; IM, 7.09±1.20 mM), HDL‐C (B,1.30±0.35 mM; IM, 1.29±0.34 mM), and LDL‐C (B, 4.91±0.95 mM; IM, 492±1.10 mM) were not significantly different between the two dietary treatments. Mean TAG levels were higher for the interesterified B‐MCT mixture (B, 1.75±0.72 mM; IM, 1.96±0.86 mM, P <0.05). We conclude that an IM of B, MCT and safflower oils as compared to native B has no appreciable effect on plasma cholesterol concentrations but is associated with a modest rise in plasma TAG.