Cytotoxic Petrosiacetylenes from the Marine Sponge  Petrosia  sp. | Zendy

Lee YeonJu | Zendy; Yoo SuJung | Zendy; Kang Jong Soon | Zendy; Yun Jieun | Zendy; Shin Hee Jae | Zendy; Lee Jong Seok | Zendy; Lee HyiSeung | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Cytotoxic Petrosiacetylenes from the Marine Sponge Petrosia sp.

Author(s) -

Lee YeonJu,

Yoo SuJung,

Kang Jong Soon,

Yun Jieun,

Shin Hee Jae,

Lee Jong Seok,

Lee HyiSeung

Publication year - 2013

Publication title -

lipids

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.601

H-Index - 120

eISSN - 1558-9307

pISSN - 0024-4201

DOI - 10.1007/s11745-012-3727-5

Subject(s) - sponge , stereochemistry , cytotoxicity , biology , cancer cell lines , cytotoxic t cell , chemistry , cancer cell , cancer , botany , biochemistry , genetics , in vitro

A novel petrosiacetylene analog (petrosiacetylene E) has been isolated from the Korean marine sponge Petrosia sp., along with petrosiacetylene A, B and C. Their structures were elucidated on the basis of spectroscopic methods and the stereochemistry of the new compound was determined by using the modified Mosher's method. Petrosiacetylene E showed higher cytotoxicity against five human cancer cell lines than petrosiacetylene A and B, presumably due to the additional hydroxy group located at C‐16.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research