Comparison of Postprandial Oleic Acid, 9 c, 11 t  CLA and 10 t, 12 c  CLA Oxidation in Healthy Moderately Overweight Subjects | Zendy

MalpuechBrugère Corinne | Zendy; Mensink Ronald P. | Zendy; Loreau Olivier | Zendy; Maret Agnès | Zendy; Fernie Claire E. | Zendy; Lassel Taous S. | Zendy; Chardigny Jean Michel | Zendy; Scrimgeour Charlie M. | Zendy; Sébédio Jean Louis | Zendy; Beaufrère Bernard | Zendy

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Comparison of Postprandial Oleic Acid, 9 c, 11 t CLA and 10 t, 12 c CLA Oxidation in Healthy Moderately Overweight Subjects

Author(s) -

MalpuechBrugère Corinne,

Mensink Ronald P.,

Loreau Olivier,

Maret Agnès,

Fernie Claire E.,

Lassel Taous S.,

Chardigny Jean Michel,

Scrimgeour Charlie M.,

Sébédio Jean Louis,

Beaufrère Bernard

Publication year - 2010

Publication title -

lipids

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.601

H-Index - 120

eISSN - 1558-9307

pISSN - 0024-4201

DOI - 10.1007/s11745-010-3480-6

Subject(s) - postprandial , oleic acid , clinical chemistry , lipidology , overweight , medicine , chemistry , oxidative metabolism , endocrinology , metabolism , biochemistry , obesity , insulin

Few studies report the individual effect of 9 c, 11 t ‐ and 10 t, 12 c ‐CLA on human energy metabolism. We compared the postprandial oxidative metabolism of 9 c, 11 t ‐ and 10 t, 12 c ‐CLA and oleic acid (9 c ‐18:1) in 22 healthy moderately overweight volunteers. After 24 weeks supplementation with 9 c, 11 t ‐ , 10 t, 12 c ‐CLA or 9 c ‐18:1 (3 g/day), subjects consumed a single oral bolus of the appropriate [1‐ 13 C]‐labeled fatty acid. 8 h post‐dose, cumulative oxidation was similar for 9 c ‐18:1 and 10 t, 12 c ( P = 0.66), but significantly higher for 9 c, 11 t ( P < 0.01).

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