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Comparison of Postprandial Oleic Acid, 9 c, 11 t CLA and 10 t, 12 c CLA Oxidation in Healthy Moderately Overweight Subjects
Author(s) -
MalpuechBrugère Corinne,
Mensink Ronald P.,
Loreau Olivier,
Maret Agnès,
Fernie Claire E.,
Lassel Taous S.,
Chardigny Jean Michel,
Scrimgeour Charlie M.,
Sébédio Jean Louis,
Beaufrère Bernard
Publication year - 2010
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/s11745-010-3480-6
Subject(s) - postprandial , oleic acid , clinical chemistry , lipidology , overweight , medicine , chemistry , oxidative metabolism , endocrinology , metabolism , biochemistry , obesity , insulin
Few studies report the individual effect of 9 c, 11 t ‐ and 10 t, 12 c ‐CLA on human energy metabolism. We compared the postprandial oxidative metabolism of 9 c, 11 t ‐ and 10 t, 12 c ‐CLA and oleic acid (9 c ‐18:1) in 22 healthy moderately overweight volunteers. After 24 weeks supplementation with 9 c, 11 t ‐ , 10 t, 12 c ‐CLA or 9 c ‐18:1 (3 g/day), subjects consumed a single oral bolus of the appropriate [1‐ 13 C]‐labeled fatty acid. 8 h post‐dose, cumulative oxidation was similar for 9 c ‐18:1 and 10 t, 12 c ( P = 0.66), but significantly higher for 9 c, 11 t ( P < 0.01).