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Pecipamide, a New Sphingosine Derivative from the Cultures of Polyporus picipes (Basidiomycetes)
Author(s) -
Li Yong,
Ma YaTuan,
Kuang Yi,
Gao JinMing,
Qin JianChun
Publication year - 2010
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/s11745-010-3413-4
Subject(s) - polyporus , lanostane , chemistry , metabolite , stereochemistry , sphingosine , nuclear magnetic resonance spectroscopy , congener , basidiomycota , organic chemistry , triterpene , botany , biology , biochemistry , medicine , alternative medicine , receptor , pathology
A new C 18 ‐ceramide congener named pecipamide ( 1 ), together with the known ergosta‐4,6,8(14),22‐tetraen‐3‐one ( 2 ), was isolated from the solid fermentations of the basidiomycetous fungus Polyporus picipes . The structure of the new metabolite was established as (2′ R ,2 S ,3 R )‐ N ‐2′‐hydroxyheptadecanoyl‐2‐amino‐octadecane‐1,3‐diol on the basis of spectroscopic data, including 1D‐ and 2D‐ nuclear magnetic resonance spectroscopy (NMR) experiments, as well as by means of mass spectrometric measurements (MS).