Premium
Novel Cyclopropane Fatty Acids from the Phospholipids of the Caribbean Sponge Pseudospongosorites suberitoides
Author(s) -
Carballeira Néstor M.,
Montano Nashbly,
Vicente Jan,
Rodriguez Abimael D.
Publication year - 2007
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/s11745-007-3047-3
Subject(s) - cyclopropane , sponge , derivatization , fatty acid , stereochemistry , chemistry , ring (chemistry) , organic chemistry , biology , botany , high performance liquid chromatography
The cyclopropane fatty acids 17‐methyl‐ trans ‐4,5‐methyleneoctadecanoic acid, 18‐methyl‐ trans ‐4,5‐methylenenonadecanoic acid, and 17‐methyl‐ trans ‐4,5‐methylenenonadecanoic acid were characterized for the first time in nature in the phospholipids (mainly PE, PG and PS) of the hermit‐crab sponge Pseudospongosorites suberitoides . Pyrrolidine derivatization was the key in identifying the position of the cyclopropyl and methyl groups in the acyl chains and 1 H NMR was used to determine the trans stereochemistry of the cyclopropane ring. The phospholipids from the sponge also contained an interesting series of iso‐anteiso Δ 5,9 fatty acids with chain‐lengths between 17 and 21 carbons, with the fatty acids (5 Z ,9 Z )‐18‐methyl‐5,9‐nonadecadienoic acid and the (5 Z ,9 Z )‐17‐methyl‐5,9‐nonadecadienoic acid being described for the first time in sponges. The anteiso α‐methoxylated fatty acid 2‐methoxy‐12‐methyltetradecanoic acid was also identified for the first time in nature in the phospholipids of this interesting marine sponge. The novel cyclopropyl fatty acids could have originated from the phospholipids of a cyanobacterium living in symbiosis with the sponge.