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Dietary conjugated linoleic acid increases endurance capacity and fat oxidation in mice during exercise
Author(s) -
Mizunoya Wataru,
Haramizu Satoshi,
Shibakusa Tetsuro,
Okabe Yuki,
Fushiki Tohru
Publication year - 2005
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/s11745-005-1381-5
Subject(s) - conjugated linoleic acid , clinical chemistry , medicine , ingestion , lipidology , endocrinology , linoleic acid , chemistry , vo2 max , respiratory exchange ratio , endurance training , lipoprotein lipase , treadmill , fatty acid , biochemistry , biology , adipose tissue , heart rate , blood pressure
Ingestion of CLA activates β‐oxidation and causes loss of body fat in rodents. We investigated the effects of dietary CLA on endurance capacity and energy metabolism during exercis in mice. Five‐week‐old male BALB/c mice were fed a control diet containing 1.0% linoleic acid or a diet containing 0.5% CLA that replaced an equivalent amount of linoleic acid for 1 wk. The maximum swimming time until fatigue was significantly higher in the CLA‐fed group than in the control group. During treadmill running, the respiratory exchange ratio was significantly lower in the CLA‐fed group, but oxygen consumption did not differ significantly between groups, suggesting that FA contributed more as an energy substrate in the CLA‐fed mice. The muscle lipoprotein lipase activity was significantly higher in the CLA‐fed group than in the control group. These results suggest that CLA ingestion increases endurance exercise capacity by promoting fat oxidation during exercise.