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Impact of dietary n−3 FA deficiency on rat bone tissue FA composition
Author(s) -
Li Yong,
Greiner Rebecca S.,
Salem Norman,
Watkins Bruce A.
Publication year - 2003
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/s11745-003-1115-8
Subject(s) - lipidology , clinical chemistry , food science , composition (language) , chemistry , linoleic acid , alpha linolenic acid , biochemistry , docosahexaenoic acid , polyunsaturated fatty acid , fatty acid , linguistics , philosophy
The effect of dietary n−3 FA deficiency on bone tissue FA composition was evaluated in growing rats. Two mixtures combining hydrogenated coconut oil with safflower oil served as the n−3‐deficient dietary treatments and provided two levels of linoleic acid (LA). The n−3 treatments were formulated with added α‐linolenic acid (LNA) from flaxseed oil (diet LNA) or LNA plus DHA, and both were balanced for LA. This study showed that bone is sensitive to changes in dietary n−3 FA and that DHA is more effective than LNA in maintaining DHA levels in these tissues.