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New glycosphingolipid containing an unusual sphingoid base from the basidiomycete Polyporus ellisii
Author(s) -
Gao JinMing,
Hu Lin,
Dong ZeJun,
Liu JiKai
Publication year - 2001
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/s11745-001-0752-2
Subject(s) - glycosphingolipid , polyporus , chemistry , glucocerebroside , chloroform , cerebroside , stereochemistry , methanol , mass spectrometry , organic chemistry , chromatography , biochemistry , glucocerebrosidase , enzyme
A new 9‐methyl‐sphinga‐4,8‐dienine‐containing glucocerebroside ( 1 ), together with two additional known analogs, cerebrosides B and D, was isolated from the chloroform‐soluble lipid fraction of the ethanol and chloroform/methanol extract of the fruiting bodies of the basidiomycete Polyporus ellisli Berk. and characterized. The structure and relative stereochemistry of the new compound were identified as (2 S ,3 R ,4 E ,8 E )‐1‐(β‐ d ‐glucopyranosyl)‐3‐hydroxy‐2‐[( R )‐2′‐hydroxyheptadecanoyl]amino‐9‐methyl‐4,8‐octadecadiene by means of spectroscopic ( 1 H, 13 C, and two‐dimensional nuclear magnetic resonance; mass spectrometry) and chemical methods.