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In vivo evaluation of the effects of continuous exercise on skeletal muscle triglycerides in trained humans
Author(s) -
RicoSanz Jesus,
Moosavi Marjan,
Louise Thomas E.,
McCarthy John,
Coutts Glyn A.,
Saeed Nadeem,
Bell Jimmy D.
Publication year - 2000
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/s11745-000-0647-2
Subject(s) - endocrinology , medicine , skeletal muscle , treadmill , gastrocnemius muscle , soleus muscle , lipidology , chemistry , leg muscle , clinical chemistry , triglyceride , anatomy , cholesterol , physical medicine and rehabilitation
Magnetic resonance spectroscopy ( 1 H MRS) and imaging (MRI) were used to investigate the effects of a bout of moderate prolonged exercise on intra (IMCL)‐ and extramyocellular lipid (EMCL) utilization in the soleus, tibialis anterior, and gastrocnemius muscles of five trained human subjects. MRI and 1 H MRS measurements were obtained before and after a 90 min run on a calibrated treadmill at a velocity corresponding to 64±1.5% of each subjects' maximal rate of oxygen consumption. There were significant decreases in IMCL following exercise in the tibialis (pre: 22.37±4.33 vs. post: 15.16±3.25 mmol/kg dry wt; P <0.01) and soleus (pre: 36.93±1.45 vs. post: 29.85 ±2.44 mmol/kg dry wt; P <0.01) muscles. There was also a decrease in the gastrocnemius muscle, although this did not reach the level of significance (pre: 33.78±5.35 vs. post: 28.48±5.44 mmol/kg dry weight; P <0.10). No significant changes were observed in EMCL or subcutaneous fat. In conclusion, this study showed that IMCL were significantly utilized in the tibialis and soleus muscles of aerobically endurance‐trained humans. The absence of significant utilization of IMCL in the gastrocnemius may reflect differences in fiber type and/or intensity of contraction for each muscle group.