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Lipid analog with 2‐nitrophenol trigger designed for liposome fusion at physiological pH
Author(s) -
Shah S. N.,
Tomohiro Takenori,
Ogawa Yoshikatsu,
Kodaka Masato,
Okuno Hiroaki
Publication year - 2000
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/s11745-000-0574-2
Subject(s) - liposome , chemistry , alkyl , fusion , lipidology , clinical chemistry , nitrophenol , biophysics , stereochemistry , biochemistry , combinatorial chemistry , organic chemistry , biology , catalysis , philosophy , linguistics
A novel lipid analog with two long alkyl (C 16 ) chains, an aspartate skeleton, a connecting alkyl (C 8 ) chain, and 2‐nitrophenol trigger group is synthesized by an efficient synthetic route, which can induce liposome fusion at physiological pH.