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Voltammetric Response and Determination of an Anti‐Inflammatory Drug at a Cationic Surfactant‐Modified Glassy Carbon Electrode
Author(s) -
Nayak Deepti S.,
Shetti Nagaraj P.
Publication year - 2016
Publication title -
journal of surfactants and detergents
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.349
H-Index - 48
eISSN - 1558-9293
pISSN - 1097-3958
DOI - 10.1007/s11743-016-1854-3
Subject(s) - chemistry , cyclic voltammetry , electrochemistry , pulmonary surfactant , differential pulse voltammetry , linear sweep voltammetry , detection limit , bromide , voltammetry , cationic polymerization , inorganic chemistry , glassy carbon , adsorption , electrode , analytical chemistry (journal) , chromatography , organic chemistry , biochemistry
Electrochemical oxidation of thiosalicylic acid in the presence of cationic surfactant, cetyl trimethylammonium bromide (CTAB), at a glassy carbon electrode was investigated. The electrochemical response of a modified sensor towards thiosalicylic acid determination was studied by the means of cyclic voltammetry, linear sweep voltammetry and differential pulse voltammetry (DPV). The liquid phase oxidation of thiosalicylic acid in the presence of CTAB leads to a notable enhancement in the peak current and a lowering of the peak potential. The electrochemical process was observed to be adsorption‐controlled, irreversible and involves oxidation of one electron. Effects of anodic peak potential ( E p ), anodic peak current ( I pa ) and heterogeneous rate constant ( k 0 ) were calculated. The linear response was obtained in the range of 1.0 µM–1.0 mM with a detection limit of 113 nM.