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Synthesis and Properties of Dicephalic Cationic Surfactants Containing a Quaternary Ammonium and a Guanidine Group
Author(s) -
Song Yongbo,
Li Qiuxiao,
Li Yunling,
Zhi Lifei
Publication year - 2013
Publication title -
journal of surfactants and detergents
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.349
H-Index - 48
eISSN - 1558-9293
pISSN - 1097-3958
DOI - 10.1007/s11743-012-1417-1
Subject(s) - chemistry , guanidine , ammonium , surface tension , cationic polymerization , alkyl , amphiphile , aqueous solution , pulmonary surfactant , antimicrobial , antibacterial activity , hydrochloride , organic chemistry , bacteria , polymer , biochemistry , biology , copolymer , genetics , physics , quantum mechanics
Novel dicephalic surfactants containing a quaternary ammonium and a guanidine group were synthesized, and the effect of the alkyl chain length on micellization and antimicrobial activity were investigated. Surface tension and conductivity were applied to study the self‐aggregation of the amphiphilic molecule in aqueous solution. The results indicated that these compounds reduce the surface tension to a level of 30–36 mN/m at the air/water interface and that there is a characteristic chain length dependence of the micellization process of surfactants. The antimicrobial activity was evaluated against Gram‐negative, Gram‐positive bacteria and fungi, indicating strong antibacterial activity against tested strains.