Open AccessAdaptive Remodeling in the Elastase-Induced Rabbit Aneurysms
Author(s) -
Chao Sang,
David F. Kallmes,
Ramanathan Kadirvel,
Michael J. Durka,
Yuqin Ding,
Daying Dai,
Simon C. Watkins,
Anne M. Robertson
Publication year - 2020
Publication title -
experimental mechanics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.815
H-Index - 87
eISSN - 1741-2765
pISSN - 0014-4851
DOI - 10.1007/s11340-020-00671-9
Subject(s) - aneurysm , elastin , adventitia , extracellular matrix , elastase , materials science , biomedical engineering , anatomy , medicine , pathology , radiology , biology , microbiology and biotechnology , biochemistry , enzyme
Rupture of brain aneurysms is associated with high fatality and morbidity rates. Through remodeling of the collagen matrix, many aneurysms can remain unruptured for decades, despite an enlarging and evolving geometry.