Open AccessEffect of Glycation on Interlamellar Bonding of Arterial Elastin
Author(s) -
R. Wang,
Xunjie Yu,
Anastasia Gkousioudi,
Yanhang Zhang
Publication year - 2020
Publication title -
experimental mechanics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.815
H-Index - 87
eISSN - 1741-2765
pISSN - 0014-4851
DOI - 10.1007/s11340-020-00644-y
Subject(s) - elastin , glycation , materials science , aorta , chemistry , biomedical engineering , diabetes mellitus , medicine , endocrinology , pathology
Interlamellar bonding in the arterial wall is often compromised by cardiovascular diseases. However, several recent nationwide and hospital-based studies have uniformly reported reduced risk of thoracic aortic dissection in patients with diabetes. As one of the primary structural constituents in the arterial wall, elastin plays an important role in providing its interlamellar structural integrity.