Open AccessSleep apnea and galectin-3: possible sex-specific relationship
Author(s) -
Malvika Singh,
Craig L. Hanis,
Susan Redline,
Christie M. Ballantyne,
Ihab Hamzeh,
David Aguilar
Publication year - 2019
Publication title -
sleep and breathing
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.907
H-Index - 63
eISSN - 1522-1709
pISSN - 1520-9512
DOI - 10.1007/s11325-019-01788-5
Subject(s) - medicine , sleep apnea , apnea , biomarker , obstructive sleep apnea , apnea–hypopnea index , sleep disorder , polysomnography , central sleep apnea , cohort , disease , cardiology , endocrinology , insomnia , psychiatry , chemistry , biochemistry
Sleep apnea is associated with increased risk of cardiovascular disease. Elevated plasma galectin-3 levels, a biomarker associated with myocardial fibrosis, are also associated with adverse cardiovascular events, including heart failure. Our objective was to determine the relationship between severity of sleep apnea and plasma levels of galectin-3 and to determine whether this relationship was modified by sex.