Vinorelbine Delivery and Efficacy in the MDA-MB-231BR Preclinical Model of Brain Metastases of Breast Cancer
Author(s) -
Ramakrishna Samala,
Helen R. Thorsheim,
Satyanarayana Goda,
Kunal S. Taskar,
Brunilde Gril,
Patricia S. Steeg,
Quentin R. Smith
Publication year - 2016
Publication title -
pharmaceutical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.815
H-Index - 206
eISSN - 1573-904X
pISSN - 0724-8741
DOI - 10.1007/s11095-016-2012-3
Subject(s) - vinorelbine , brain metastasis , medicine , in vivo , metastasis , breast cancer , systemic administration , cancer , brain tumor , pathology , blood–brain barrier , evans blue , biomarker , pharmacology , chemotherapy , central nervous system , chemistry , biology , biochemistry , microbiology and biotechnology , cisplatin
To evaluate vinorelbine drug exposure and activity in brain metastases of the human MDA-MB-231BR breast cancer model using integrated imaging and analysis.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom