Open AccessBiodistribution and Efficacy of Low Temperature-Sensitive Liposome Encapsulated Docetaxel Combined with Mild Hyperthermia in a Mouse Model of Prostate Cancer
Author(s) -
Ashish Ranjan,
Compton J. Benjamin,
Ayele H. Negussie,
Saurin Chokshi,
Paul H. Chung,
Dmitry Volkin,
Nitin Yeram,
W. Marston Linehan,
Matthew R. Dreher,
Peter A. Pinto,
Bradford J. Wood
Publication year - 2016
Publication title -
pharmaceutical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.815
H-Index - 206
eISSN - 1573-904X
pISSN - 0724-8741
DOI - 10.1007/s11095-016-1971-8
Subject(s) - docetaxel , hyperthermia , biodistribution , prostate cancer , medicine , prostate , saline , cancer , urology , chemistry , cancer research , pharmacology , in vitro , biochemistry
Low temperature sensitive liposome (LTSL) encapsulated docetaxel were combined with mild hyperthermia (40-42°C) to investigate in vivo biodistribution and efficacy against a castrate resistant prostate cancer.