Open AccessIn Silico Prediction of Percutaneous Absorption and Disposition Kinetics of Chemicals
Author(s) -
Longjian Chen,
Lujia Han,
Ouarda Saib,
Guoping Lian
Publication year - 2014
Publication title -
pharmaceutical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.815
H-Index - 206
eISSN - 1573-904X
pISSN - 0724-8741
DOI - 10.1007/s11095-014-1575-0
Subject(s) - in silico , kinetics , disposition , chemistry , absorption (acoustics) , pharmacology , pharmacokinetics , medicine , biochemistry , materials science , psychology , physics , quantum mechanics , composite material , gene , social psychology
To develop in-silico model for predicting percutaneous absorption and disposition kinetics of chemicals in skin layers so as to facilitate the design of transdermal drug delivery systems and skin care products, and risk assessment of occupational or consumer exposure.
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