Decoupling the Contribution of Surface Energy and Surface Area on the Cohesion of Pharmaceutical Powders
Author(s) -
Umang V. Shah,
Dolapo Olusanmi,
Ajit S. Narang,
Munir Hussain,
Mike Tobyn,
Steven J. Hinder,
Jerry Y. Y. Heng
Publication year - 2014
Publication title -
pharmaceutical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.815
H-Index - 206
eISSN - 1573-904X
pISSN - 0724-8741
DOI - 10.1007/s11095-014-1459-3
Subject(s) - cohesion (chemistry) , surface energy , pharmaceutical technology , decoupling (probability) , mineralogy , materials science , chemistry , composite material , chromatography , engineering , organic chemistry , control engineering
Surface area and surface energy of pharmaceutical powders are affected by milling and may influence formulation, performance and handling. This study aims to decouple the contribution of surface area and surface energy, and to quantify each of these factors, on cohesion.
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