Open AccessRate of change in maximum 18F-FDOPA PET uptake and non-enhancing tumor volume predict malignant transformation and overall survival in low-grade gliomas
Author(s) -
Talia C. Oughourlian,
Jingwen Yao,
Jacob Schlossman,
Catalina Raymond,
Matthew Ji,
Hiroyuki Tatekawa,
Noriko Salamon,
Whitney Pope,
Johannes Czernin,
Phioanh Leia Nghiemphu,
Albert Lai,
Timothy F. Cloughesy,
Benjamin M. Ellingson
Publication year - 2020
Publication title -
journal of neuro-oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.256
H-Index - 114
eISSN - 1573-7373
pISSN - 0167-594X
DOI - 10.1007/s11060-020-03407-w
Subject(s) - fluid attenuated inversion recovery , medicine , nuclear medicine , glioma , proportional hazards model , positron emission tomography , standardized uptake value , univariate analysis , oncology , magnetic resonance imaging , radiology , multivariate analysis , cancer research
To examine whether the rate of change in maximum 18 F-FDOPA PET uptake and the rate of change in non-enhancing tumor volume could predict malignant transformation and residual overall survival (OS) in low grade glioma (LGG) patients who received serial 18 F-FDOPA PET and MRI scans.