Open AccessTreatment of dedifferentiated chordoma: a retrospective study from a large volume cancer center
Author(s) -
Ryan Nachwalter,
Robert J. Rothrock,
E. Katsoulakis,
Mrinal M. Gounder,
Patrick J. Boland,
Mark H. Bilsky,
Ilya Laufer,
Adam Schmitt,
Yoshiya Yamada,
Daniel S. Higginson
Publication year - 2019
Publication title -
journal of neuro-oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.256
H-Index - 114
eISSN - 1573-7373
pISSN - 0167-594X
DOI - 10.1007/s11060-019-03239-3
Subject(s) - medicine , retrospective cohort study , cohort , cancer , survival analysis , radiation therapy , surgery
Dedifferentiated chordomas (DC) are genetically and clinically distinct from conventional chordomas (CC), exhibiting frequent SMARCB1 alterations and a more aggressive clinical course. We compared treatment and outcomes of DC and CC patients in a retrospective cohort study from a single, large-volume cancer center.