Open AccessHigh-dose radiation therapy is needed for intracranial control and long-term survival in patients with non-seminomatous germ cell tumor brain metastases
Author(s) -
Dana L. Casey,
Kenneth L. Pitter,
Brandon S. Imber,
Andrew Lin,
Timothy A. Chan,
Kathryn Beal,
Yoshiya Yamada,
Darren R. Feldman,
T. Jonathan Yang
Publication year - 2019
Publication title -
journal of neuro-oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.256
H-Index - 114
eISSN - 1573-7373
pISSN - 0167-594X
DOI - 10.1007/s11060-019-03123-0
Subject(s) - medicine , proportional hazards model , radiation therapy , hazard ratio , regimen , germ cell tumors , multivariate analysis , oncology , chemotherapy , surgery , urology , radiology , confidence interval
The presence of brain metastases (BM) in patients with non-seminomatous germ cell tumor (NSGCT) is associated with poor prognosis. While radiation therapy (RT) is an important treatment for patients with NSGCT BM, there is a paucity of data on the optimal regimen. We sought to investigate the impact of RT on clinical outcomes in patients with NSGCT BM.