Open AccessRacial/ethnic disparities and incidence of malignant peripheral nerve sheath tumors: results from the Surveillance, Epidemiology, and End Results Program, 2000–2014
Author(s) -
Erin C. PeckhamGregory,
Roberto Montenegro,
David A. Stevenson,
David Viskochil,
Michael E. Scheurer,
Philip J. Lupo,
Joshua D. Schiffman
Publication year - 2018
Publication title -
journal of neuro-oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.256
H-Index - 114
eISSN - 1573-7373
pISSN - 0167-594X
DOI - 10.1007/s11060-018-2842-4
Subject(s) - incidence (geometry) , medicine , epidemiology , ethnic group , demography , surveillance, epidemiology, and end results , confidence interval , malignant peripheral nerve sheath tumor , rate ratio , cancer registry , physics , immunohistochemistry , sociology , anthropology , optics
Malignant peripheral nerve sheath tumors (MPNSTs) are rare tumors, generally high-grade, and comprise ~ 5-10% of soft tissue sarcomas. Over two-thirds of MPNSTs metastasize, and upwards of 40% clinically recur. Etiologic risk factors for MPNSTs are historically understudied. There is evidence to suggest MPNST incidence differs across racial/ethnic groups in pediatric populations. Therefore, we sought to estimate differences in MPNST incidence by race/ethnicity among all ages in the United States.