Visualization technologies for 5-ALA-based fluorescence-guided surgeries | Zendy

Linpeng Wei | Zendy; David W. Roberts | Zendy; Nader Sanai | Zendy; Jonathan Liu | Zendy

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Visualization technologies for 5-ALA-based fluorescence-guided surgeries

Author(s) -

Linpeng Wei,

David W. Roberts,

Nader Sanai,

Jonathan Liu

Publication year - 2018

Publication title -

journal of neuro-oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.256

H-Index - 114

eISSN - 1573-7373

pISSN - 0167-594X

DOI - 10.1007/s11060-018-03077-9

Subject(s) - visualization , glioma , biomedical engineering , computer science , resection , fluorescence microscope , medical physics , medicine , artificial intelligence , fluorescence , surgery , cancer research , optics , physics

5-ALA-based fluorescence-guided surgery has been shown to be a safe and effective method to improve intraoperative visualization and resection of malignant gliomas. However, it remains ineffective in guiding the resection of lower-grade, non-enhancing, and deep-seated tumors, mainly because these tumors do not produce detectable fluorescence with conventional visualization technologies, namely, wide-field (WF) surgical microscopy.

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