Open AccessAdverse Pregnancy Outcomes Following the Assassination of John F. Kennedy in 1963
Author(s) -
Alexa A. Freedman,
Gregory E. Miller,
Lauren Keenan-Devlin,
Britney P. Smart,
Janedelie Romero,
Ann Borders,
Linda M. Ernst
Publication year - 2021
Publication title -
maternal and child health journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1
H-Index - 85
eISSN - 1573-6628
pISSN - 1092-7875
DOI - 10.1007/s10995-021-03139-x
Subject(s) - medicine , pregnancy , odds ratio , obstetrics , hazard ratio , prospective cohort study , cohort study , sibling , confounding , in utero , fetus , confidence interval , psychology , genetics , biology , developmental psychology
Women exposed to stressful events during pregnancy are thought to be at increased risk of adverse birth outcomes. However, studies investigating stressful events are often unable to control for important confounders, such as behavioral and genetic characteristics, or to isolate the impact of the stressor from other secondary effects. We used a discordant-sibling design, which provides stronger inferences about causality, to examine whether a widespread stressor with limited impact on day-to-day life (John F. Kennedy assassination) resulted in an increased risk of adverse birth outcomes.