Investigation of a Sensing Strategy Based on a Nucleophilic Addition Reaction for Quantitative Detection of Bisulfite (HSO3−) | Zendy

Keith R. Everitt | Zendy; Hannah C. Schmitz | Zendy; Amanda J. Macke | Zendy; Jinqing Shan | Zendy; Eunju Jang | Zendy; Brandon E. Luedtke | Zendy; Kimberly A. Carlson | Zendy; Haishi Cao | Zendy

Open Access

Investigation of a Sensing Strategy Based on a Nucleophilic Addition Reaction for Quantitative Detection of Bisulfite (HSO3−)

Author(s) -

Keith R. Everitt,

Hannah C. Schmitz,

Amanda J. Macke,

Jinqing Shan,

Eunju Jang,

Brandon E. Luedtke,

Kimberly A. Carlson,

Haishi Cao

Publication year - 2020

Publication title -

journal of fluorescence

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.372

H-Index - 71

eISSN - 1573-4994

pISSN - 1053-0509

DOI - 10.1007/s10895-020-02599-8

Subject(s) - chemistry , bisulfite , nucleophile , aqueous medium , aqueous solution , nucleophilic addition , absorption (acoustics) , sensitivity (control systems) , photochemistry , combinatorial chemistry , organic chemistry , catalysis , biochemistry , optics , gene expression , physics , dna methylation , gene , electronic engineering , engineering

A reaction-based sensor (NAS-1) showed a high affinity and sensitivity to HSO3- via a nucleophilic addition reaction in the aqueous media, giving dual signals from absorption and emission spectra. NAS-1 was successfully applied in RK13 epithelial cells to detect HSO3- in a cellular environment.

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