Open AccessInvestigation of a Sensing Strategy Based on a Nucleophilic Addition Reaction for Quantitative Detection of Bisulfite (HSO3−)
Author(s) -
Keith R. Everitt,
Hannah C. Schmitz,
Amanda J. Macke,
Jinqing Shan,
Eun-Ju Jang,
Brandon E. Luedtke,
Kimberly A. Carlson,
Haishi Cao
Publication year - 2020
Publication title -
journal of fluorescence
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.372
H-Index - 71
eISSN - 1573-4994
pISSN - 1053-0509
DOI - 10.1007/s10895-020-02599-8
Subject(s) - chemistry , bisulfite , nucleophile , aqueous medium , aqueous solution , nucleophilic addition , absorption (acoustics) , sensitivity (control systems) , photochemistry , combinatorial chemistry , organic chemistry , catalysis , biochemistry , optics , gene expression , physics , dna methylation , gene , electronic engineering , engineering
A reaction-based sensor (NAS-1) showed a high affinity and sensitivity to HSO3- via a nucleophilic addition reaction in the aqueous media, giving dual signals from absorption and emission spectra. NAS-1 was successfully applied in RK13 epithelial cells to detect HSO3- in a cellular environment.