The Relationship Between Mucosal Microbiota, Colitis, and Systemic Inflammation in Chronic Granulomatous Disorder | Zendy

Mehmet Davrandi | Zendy; Stephanie Harris | Zendy; Philip J Smith | Zendy; Charles Murray | Zendy; David M. Lowe | Zendy

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The Relationship Between Mucosal Microbiota, Colitis, and Systemic Inflammation in Chronic Granulomatous Disorder

Author(s) -

Mehmet Davrandi,

Stephanie Harris,

Philip J Smith,

Charles Murray,

David M. Lowe

Publication year - 2021

Publication title -

journal of clinical immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.739

H-Index - 96

eISSN - 1573-2592

pISSN - 0271-9142

DOI - 10.1007/s10875-021-01165-6

Subject(s) - colitis , microbiome , calprotectin , immunology , pathogenesis , ulcerative colitis , inflammation , inflammatory bowel disease , gut flora , medicine , gastroenterology , biology , disease , bioinformatics

Chronic granulomatous disorder (CGD) is a primary immunodeficiency which is frequently complicated by inflammatory colitis and is associated with systemic inflammation. Herein, we aimed to investigate the role of the microbiome in the pathogenesis of colitis and systemic inflammation.

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