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Clinical Significance of Serum HMGB-1 and sRAGE Levels in Systemic Sclerosis: Association with Disease Severity
Author(s) -
Ayumi Yoshizaki,
Kazuhiro Komura,
Yohei Iwata,
Fumihide Ogawa,
Toshihide Hara,
Eiji Muroi,
Motoi Takenaka,
Kazuhiro Shimizu,
Minoru Hasegawa,
Manabu Fujimoto,
Shinichi Sato
Publication year - 2008
Publication title -
journal of clinical immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.739
H-Index - 96
eISSN - 1573-2592
pISSN - 0271-9142
DOI - 10.1007/s10875-008-9252-x
Subject(s) - medicine , rage (emotion) , immune system , scleroderma (fungus) , disease , immunology , biology , neuroscience , inoculation
The high mobility group box 1 protein (HMGB-1)/advanced glycation end products (RAGE) system is recently shown to play an important part in immune/inflammatory disorders. However, the association of this system in systemic sclerosis (SSc) remains unknown.

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