Open AccessInfluence of electromagnetic waves, with maxima in the green or red range, on the morphofunctional properties of multipotent stem cells
Author(s) -
А. С. Чернов,
D. A. Reshetnikov,
G. K. Ristsov,
Yu. A. Kovalitskaya,
А. М. Ермаков,
A. A. Manokhin,
Alexander V. Simakin,
Р. Г. Василов,
Sergey V. Gudkov
Publication year - 2019
Publication title -
journal of biological physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.318
H-Index - 46
eISSN - 1573-0689
pISSN - 0092-0606
DOI - 10.1007/s10867-019-09531-7
Subject(s) - photostimulation , mesenchymal stem cell , stem cell , stromal cell , biophysics , electromagnetic radiation , multipotent stem cell , optogenetics , hydrogen peroxide , microbiology and biotechnology , chemistry , biology , optics , biochemistry , physics , neuroscience , cancer research , progenitor cell
This paper examines the effect of electromagnetic waves, with maxima in the green or red regions of the spectrum, on the morphofunctional state of multipotent mesenchymal stromal cells. The illumination regimes used in our experiments did not lead to any substantial heating of the samples; the physical parameters of the lighting were carefully monitored. When the samples were illuminated with a green light, no significant photostimulatory effect was observed. Red light, on the other hand, had an evident photostimulatory effect. It is shown that photostimulation with a red light decreases the enzymatic activities of mitochondrial dehydrogenases and enhances the viability of cells, their proliferative activity, and their ability to form bone tissue. It is also established that red light stimulates cell proliferation, while not activating the genes that increase the risk of the subsequent malignant transformation of cells or their death. This paper discusses the possible role of hydrogen peroxide in the processes examined.