Open AccessAlbumin used in human IVF contain different levels of lipids and modify embryo and fetal growth in a mouse model
Author(s) -
Deirdre Zander-Fox,
Lauren Villarosa,
Nicole O. McPherson
Publication year - 2021
Publication title -
journal of assisted reproduction and genetics
Language(s) - English
Resource type - Journals
eISSN - 1573-7330
pISSN - 1058-0468
DOI - 10.1007/s10815-021-02255-5
Subject(s) - blastocyst , embryo , embryo culture , embryo quality , biology , fetus , human serum albumin , embryogenesis , fatty acid , andrology , biochemistry , zygote , chemistry , genetics , pregnancy , medicine
Different commercial human embryo culture mediums can alter embryo quality and change birthweight. One component that could be contributing to variations but is not widely investigated is human serum albumin (HSA). HSA plays a multitude of roles during embryo culture and is a carrier for molecules including lipids. It remains unclear if lipid composition of HSA varies among commercial products and its effects on embryo quality, implantation, and fetal outcomes are relatively unknown.