
Altered redox status may contribute to aberrant folliculogenesis and poor reproductive outcomes in women with polycystic ovary syndrome
Author(s) -
Aalaap Naigaonkar,
Roshan Dadachanji,
Indira Hinduja,
Srabani Mukherjee
Publication year - 2021
Publication title -
journal of assisted reproduction and genetics
Language(s) - English
Resource type - Journals
eISSN - 1573-7330
pISSN - 1058-0468
DOI - 10.1007/s10815-021-02241-x
Subject(s) - polycystic ovary , follicular fluid , folliculogenesis , biology , endocrinology , medicine , insulin resistance , oocyte , embryo quality , andrology , oxidative stress , glutathione , glutathione reductase , anti müllerian hormone , glutathione peroxidase , superoxide dismutase , embryo , hormone , insulin , embryogenesis , biochemistry , microbiology and biotechnology , enzyme
Women with polycystic ovary syndrome (PCOS) are often infertile and opt for artificial reproductive techniques (ART) to conceive. Disrupted pro-/antioxidant balance in oocyte microenvironment may contribute towards sub-optimal oocyte/embryo quality and poor ART outcome in them.