Outcome prediction of microdissection testicular sperm extraction based on extracellular vesicles piRNAs | Zendy

Haicheng Chen | Zendy; Yun Xie | Zendy; Yanqing Li | Zendy; Chi Zhang | Zendy; Linyan Lv | Zendy; Jiahui Yao | Zendy; Chunhua Deng | Zendy; Xiangzhou Sun | Zendy; Xueg Zou | Zendy; Guihua Liu | Zendy

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Outcome prediction of microdissection testicular sperm extraction based on extracellular vesicles piRNAs

Author(s) -

Haicheng Chen,

Yun Xie,

Yanqing Li,

Chi Zhang,

Linyan Lv,

Jiahui Yao,

Chunhua Deng,

Xiangzhou Sun,

Xueg Zou,

Guihua Liu

Publication year - 2021

Publication title -

journal of assisted reproduction and genetics

Language(s) - English

Resource type - Journals

eISSN - 1573-7330

pISSN - 1058-0468

DOI - 10.1007/s10815-021-02101-8

Subject(s) - sperm , logistic regression , andrology , biology , testicular sperm extraction , extracellular vesicles , cohort , azoospermia , microdissection , intracytoplasmic sperm injection , medicine , in vitro fertilisation , embryo , genetics , infertility , microbiology and biotechnology , pregnancy , gene

Microdissection testicular sperm extraction (micro-TESE) could retrieve sperm from the testicles to help the non-obstructive azoospermia (NOA) patients to get their biological children, but also would cause damage to the testicles. Therefore, it is necessary to preoperatively predict the micro-TESE outcome in NOA patients. For this purpose, we aim to develop a model based on extracellular vesicles' (EVs) piRNAs (EV-piRNAs) in seminal plasma.

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