Open AccessSevere ovarian hyperstimulation syndrome associated with long-acting GnRH agonist in oncofertility patients
Author(s) -
Jacob Christ,
Christopher N. Herndon,
Bo Yu
Publication year - 2021
Publication title -
journal of assisted reproduction and genetics
Language(s) - English
Resource type - Journals
eISSN - 1573-7330
pISSN - 1058-0468
DOI - 10.1007/s10815-020-02051-7
Subject(s) - ovarian hyperstimulation syndrome , agonist , medicine , controlled ovarian hyperstimulation , gynecology , pregnancy , endocrinology , in vitro fertilisation , biology , receptor , genetics
To report three cases of severe ovarian hyperstimulation syndrome (OHSS) among oncofertility patients receiving a long-acting GnRH agonist for ovarian suppression after controlled ovarian hyperstimulation (COH) with a GnRH antagonist protocol METHODS: Chart abstraction was completed for three patients at a single academic medical center. Patients included were undergoing fertility preservation prior to gonadotoxic chemotherapy. All patients underwent COH with GnRH antagonist protocol and embryo cryopreservation immediately followed by ovarian suppression with long-acting GnRH agonist. Main outcome measure was development of OHSS.