Open AccessICSI for non-male factor: do we practice what we preach?
Author(s) -
Alexander Quaas
Publication year - 2020
Publication title -
journal of assisted reproduction and genetics
Language(s) - English
Resource type - Journals
eISSN - 1573-7330
pISSN - 1058-0468
DOI - 10.1007/s10815-020-02016-w
Subject(s) - intracytoplasmic sperm injection , reproductive medicine , medicine , male infertility , odds , gynecology , infertility , in vitro fertilisation , pregnancy , andrology , obstetrics , biology , logistic regression , genetics
Since its introduction in 1992, intracytoplasmic sperm injection (ICSI) has revolutionized the treatment of infertility due to severe male factor. Over the last three decades, the use of ICSI for non-male factor has increased dramatically, despite guidelines to the contrary from professional societies. Excessive utilization of ICSI is primarily due to an irrational fear of total fertilization failure, which is at odds with rational evidence to support its use.