Melatonin levels and microRNA (miRNA) relative expression profile in the follicular ambient microenvironment in patients undergoing in vitro fertilization process | Zendy

Haroon Latif Khan | Zendy; Shahzad Bhatti | Zendy; Sana Abbas | Zendy; Celal Kaloğlu | Zendy; Syeda Qurat-ul-Ain Zahra | Zendy; Yousaf Latif Khan | Zendy; Zahira Hassan | Zendy; Nilgün Öztürk Turhan | Zendy; Hikmet Hakan Aydın | Zendy

Open Access

Melatonin levels and microRNA (miRNA) relative expression profile in the follicular ambient microenvironment in patients undergoing in vitro fertilization process

Author(s) -

Haroon Latif Khan,

Shahzad Bhatti,

Sana Abbas,

Celal Kaloğlu,

Syeda Qurat-ul-Ain Zahra,

Yousaf Latif Khan,

Zahira Hassan,

Nilgün Öztürk Turhan,

Hikmet Hakan Aydın

Publication year - 2020

Publication title -

journal of assisted reproduction and genetics

Language(s) - English

Resource type - Journals

eISSN - 1573-7330

pISSN - 1058-0468

DOI - 10.1007/s10815-020-02010-2

Subject(s) - melatonin , follicular fluid , embryo quality , andrology , human fertilization , oxidative stress , oocyte , biology , in vitro fertilisation , follicular phase , embryo , microrna , endocrinology , reproductive medicine , medicine , pregnancy , genetics , gene

Intrafollicular fluid (IFF) melatonin plays a decisive role in maintaining granulosa cells' DNA integrity and protects them against apoptosis. It reduces oxidative stress and improves the oocyte quality with a higher fertilization rate.

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