Open AccessAntenatal antioxidants to avert autism?
Author(s) -
Alexander Quaas,
W.G. Kearns
Publication year - 2020
Publication title -
journal of assisted reproduction and genetics
Language(s) - English
Resource type - Journals
eISSN - 1573-7330
pISSN - 1058-0468
DOI - 10.1007/s10815-020-01982-5
Subject(s) - autism , reproductive medicine , oxidative stress , medicine , incidence (geometry) , bioinformatics , human genetics , pregnancy , genetics , biology , psychiatry , gene , physics , optics
Paternally derived de novo mutations (DNMs) caused by oxidative stress (OS) have been implicated in the development of autism spectrum disorders (ASDs). Whether preconception antioxidant supplementation can reduce the incidence of ASDs by reducing OS is an area of uncertainty and potentially important future scientific investigation.