The effect of laser-assisted hatching on the methylation and expression pattern of imprinted gene IGF2/H19 in mouse blastocysts and offspring | Zendy

Peng Huo | Zendy; Kai Deng | Zendy; Lulu Wang | Zendy; Man Li | Zendy; Jun Yao | Zendy; Jianghua Le | Zendy; Xiaocan Lei | Zendy; Shun Zhang | Zendy

Open Access

The effect of laser-assisted hatching on the methylation and expression pattern of imprinted gene IGF2/H19 in mouse blastocysts and offspring

Author(s) -

Peng Huo,

Kai Deng,

Lulu Wang,

Man Li,

Jun Yao,

Jianghua Le,

Xiaocan Lei,

Shun Zhang

Publication year - 2020

Publication title -

journal of assisted reproduction and genetics

Language(s) - English

Resource type - Journals

eISSN - 1573-7330

pISSN - 1058-0468

DOI - 10.1007/s10815-020-01975-4

Subject(s) - andrology , offspring , hatching , genomic imprinting , biology , imprinting (psychology) , methylation , dna methylation , blastocyst , placenta , bisulfite sequencing , gene expression , embryo , embryogenesis , pregnancy , fetus , medicine , gene , genetics , zoology

This study aimed to determine the effects of drilling and thinning treatment of laser-assisted hatching on the expression and methylation of imprinted gene IGF2/H19 in embryos and offspring.

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