Open AccessSuccessful in vitro fertilization in women with Fontan physiology
Author(s) -
Yuli Y. Kim,
Lisa D. Levine,
Sara L. Partington,
Prakash A. Patel,
Emily Ruckdeschel,
Suneeta Senapati,
Clarisa R. Gracia
Publication year - 2020
Publication title -
journal of assisted reproduction and genetics
Language(s) - English
Resource type - Journals
eISSN - 1573-7330
pISSN - 1058-0468
DOI - 10.1007/s10815-020-01969-2
Subject(s) - medicine , heart disease , infertility , pregnancy , in vitro fertilisation , fontan procedure , fertility preservation , miscarriage , fertility , biology , population , genetics , environmental health
Patients with single ventricle anatomy palliated with Fontan operation are at risk for thromboembolism, arrhythmia, and heart failure rendering pregnancy high risk or even contraindicated. Infertility and high rates of first trimester miscarriage are not uncommon. In vitro fertilization (IVF) with or without gestational surrogacy can be an option, but poses risks during ovarian stimulation, oocyte retrieval, and the post-procedural period. We present six cases of women with complex congenital heart disease status post Fontan operation who underwent successful IVF.