Open AccessPartial-AZFc deletions in Chilean men with primary spermatogenic impairment: gene dosage and Y-chromosome haplogroups
Author(s) -
María Cecilia Lardone,
Victoria Ortega,
Eliana Ortíz,
Martha Flórez,
Antonio Piottante,
Mauricio Ebensperger,
Sergio Flores,
Patricio Pezo,
Michael OrellanaSoto,
Mauricio Moraga,
Andrea Castro
Publication year - 2020
Publication title -
journal of assisted reproduction and genetics
Language(s) - English
Resource type - Journals
eISSN - 1573-7330
pISSN - 1058-0468
DOI - 10.1007/s10815-020-01957-6
Subject(s) - haplogroup , biology , y chromosome , male infertility , genetics , spermatogenesis , sertoli cell , population , andrology , haplotype , genotype , gene , infertility , medicine , endocrinology , pregnancy , environmental health
To investigate the association of partial-AZFc deletions in Chilean men with primary spermatogenic failure and their testicular histopathological phenotypes, analyzing the contribution of DAZ dosage, CDY1 copies, and Y-chromosome haplogroups.