
Healthy live births from transfer of low-mosaicism embryos after preimplantation genetic testing for aneuploidy
Author(s) -
ChunI Lee,
EnHui Cheng,
MawSheng Lee,
PinYao Lin,
YiChun Chen,
ChienHong Chen,
Lii-Shung Huang,
ChunChia Huang,
Tsung-Hsien Lee
Publication year - 2020
Publication title -
journal of assisted reproduction and genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.966
H-Index - 75
eISSN - 1573-7330
pISSN - 1058-0468
DOI - 10.1007/s10815-020-01876-6
Subject(s) - blastocyst , aneuploidy , embryo , andrology , embryo transfer , biology , in vitro fertilisation , single embryo transfer , ploidy , genetic testing , live birth , pregnancy , gynecology , obstetrics , medicine , genetics , chromosome , embryogenesis , gene
This study evaluated the potential viability of embryos with low mosaicism level (< 50%) by comparing the clinical outcomes of single mosaic versus euploid blastocyst transfer. In addition, the live birth outcomes for various types of mosaicism with respect to abnormalities in chromosome structure and content were analyzed.