Open AccessThe impact of polycystic ovary syndrome and body mass index on the absorption of recombinant human follicle stimulating hormone
Author(s) -
Malinda S. Lee,
Andrea Lanes,
Andrey V. Dolinko,
Alexandra Bailin,
Elizabeth S. Ginsburg
Publication year - 2020
Publication title -
journal of assisted reproduction and genetics
Language(s) - English
Resource type - Journals
eISSN - 1573-7330
pISSN - 1058-0468
DOI - 10.1007/s10815-020-01865-9
Subject(s) - polycystic ovary , overweight , medicine , endocrinology , follicle stimulating hormone , area under the curve , body mass index , obesity , hormone , luteinizing hormone , insulin resistance
Women with polycystic ovary syndrome (PCOS) have an increased ovarian responsiveness to exogenous recombinant follicle stimulating hormone (rFSH) but also have high rates of obesity, which is known to affect serum FSH concentrations following exogenous injection. The purpose of this study was to compare rFSH absorption and ovarian response between lean and overweight/obese PCOS subjects and normo-ovulatory controls.