Navigating the body of literature assessing BRCA1/2 mutations and markers of ovarian function: a systematic review and meta-analysis | Zendy

Christi. Cordeiro Mitchell | Zendy; Bailey McGuinness | Zendy; Eliana Fine | Zendy; W.G. Kearns | Zendy; Mindy S. Christianson | Zendy; James H. Segars | Zendy; Lisa M. Pastore | Zendy

Open Access

Navigating the body of literature assessing BRCA1/2 mutations and markers of ovarian function: a systematic review and meta-analysis

Author(s) -

Christi. Cordeiro Mitchell,

Bailey McGuinness,

Eliana Fine,

W.G. Kearns,

Mindy S. Christianson,

James H. Segars,

Lisa M. Pastore

Publication year - 2020

Publication title -

journal of assisted reproduction and genetics

Language(s) - English

Resource type - Journals

eISSN - 1573-7330

pISSN - 1058-0468

DOI - 10.1007/s10815-020-01745-2

Subject(s) - meta analysis , ovarian reserve , ovarian cancer , oncology , breast cancer , gynecology , controlled ovarian hyperstimulation , medicine , reproductive medicine , anti müllerian hormone , bioinformatics , biology , in vitro fertilisation , cancer , genetics , pregnancy , hormone , infertility

Twelve percent of women in the USA will develop invasive breast cancer in their lifetime, and that risk increases to 80% if they carry a BRCA1 or BRCA2 mutation. BRCA1/2 mutations are thought to potentially affect ovarian reserve and/or fertility.

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