Open AccessA homozygous nonsense mutation of PLCZ1 cause male infertility with oocyte activation deficiency
Author(s) -
Fengsong Wang,
Jingjing Zhang,
Shuai Kong,
Chanjuan Li,
Zhiguo Zhang,
Xiaojin He,
Huan Wu,
Dongdong Tang,
Xiaomin Zha,
Qing Tan,
Zongliu Duan,
Yunxia Cao,
Fuxi Zhu
Publication year - 2020
Publication title -
journal of assisted reproduction and genetics
Language(s) - English
Resource type - Journals
eISSN - 1573-7330
pISSN - 1058-0468
DOI - 10.1007/s10815-020-01719-4
Subject(s) - andrology , male infertility , biology , nonsense mutation , infertility , human fertilization , intracytoplasmic sperm injection , sanger sequencing , sperm , genetics , oocyte , mutation , pregnancy , medicine , missense mutation , embryo , gene
To identify the pathogenic PLCZ1 mutation involved in male infertility and fertilization failure.