Interchromosomal effect in carriers of translocations and inversions assessed by preimplantation genetic testing for structural rearrangements (PGT-SR) | Zendy

Emilia Mateu | Zendy; Lorena Rodrigo | Zendy; Vanessa Peinado | Zendy; Amparo Mercader | Zendy; Inmaculada CamposGalindo | Zendy; F. Bronet | Zendy; Sandra García-Herrero | Zendy; M. Florensa | Zendy; Miguel Milán | Zendy; C. Rubio | Zendy

Open Access

Interchromosomal effect in carriers of translocations and inversions assessed by preimplantation genetic testing for structural rearrangements (PGT-SR)

Author(s) -

Emilia Mateu,

Lorena Rodrigo,

Vanessa Peinado,

Amparo Mercader,

Inmaculada CamposGalindo,

F. Bronet,

Sandra García-Herrero,

M. Florensa,

Miguel Milán,

C. Rubio

Publication year - 2019

Publication title -

journal of assisted reproduction and genetics

Language(s) - English

Resource type - Journals

eISSN - 1573-7330

pISSN - 1058-0468

DOI - 10.1007/s10815-019-01593-9

Subject(s) - chromosomal translocation , genetics , human genetics , biology , reproductive medicine , genetic testing , computational biology , gene , pregnancy

Balanced carriers of structural rearrangements have an increased risk of unbalanced embryos mainly due to the production of unbalanced gametes during meiosis. Aneuploidy for other chromosomes not involved in the rearrangements has also been described. The purpose of this work is to know if the incidence of unbalanced embryos, interchromosomal effect (ICE) and clinical outcomes differ in carriers of different structural rearrangements.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research