Open AccessNovel compound heterozygous mutations in WEE2 causes female infertility and fertilization failure
Author(s) -
Xiaopei Zhou,
Lixia Zhu,
Meiqi Hou,
Yanling Wu,
Li Zhou,
Jiarui Wang,
Zhenxing Li,
Dazhi Zhang,
Jin Liu,
Xianqin Zhang
Publication year - 2019
Publication title -
journal of assisted reproduction and genetics
Language(s) - English
Resource type - Journals
eISSN - 1573-7330
pISSN - 1058-0468
DOI - 10.1007/s10815-019-01553-3
Subject(s) - compound heterozygosity , sanger sequencing , biology , male infertility , genetics , infertility , mutant , gene , intracytoplasmic sperm injection , pronucleus , mutation , human fertilization , gene mutation , microbiology and biotechnology , andrology , medicine , embryogenesis , zygote , pregnancy
To identify the disease-causing gene in a family with female infertility and fertilization failure.