Open AccessPharmacological administration of recombinant human AMH rescues ovarian reserve and preserves fertility in a mouse model of chemotherapy, without interfering with anti-tumoural effects
Author(s) -
Hadassa Roness,
Itay Spector,
Yael LeichtmannBardoogo,
Angela Maria Savino,
Sanaz Dereh-Haim,
Dror Meirow
Publication year - 2019
Publication title -
journal of assisted reproduction and genetics
Language(s) - English
Resource type - Journals
eISSN - 1573-7330
pISSN - 1058-0468
DOI - 10.1007/s10815-019-01507-9
Subject(s) - ovarian reserve , anti müllerian hormone , ovary , biology , ovarian follicle , follicle , fertility preservation , endocrinology , medicine , in vivo , population , hormone , fertility , infertility , pregnancy , genetics , microbiology and biotechnology , environmental health
To determine whether pharmacological administration of recombinant human anti-Mullerian hormone (rAMH) protects the ovarian reserve and preserves fertility without interfering with anti-tumoural cytotoxic action of chemotherapy.