Lack of association between genetic variants in the mannose-binding lectin 2 (MBL2) gene and HPV infection | Zendy

Paola Parrella | Zendy; Davide Seripa | Zendy; Maria G. Matera | Zendy; Monica Rinaldi | Zendy; Emanuela Signori | Zendy; Carolina Gravina | Zendy; Antonietta Pia Gallo | Zendy; Maria Prencipe | Zendy; Elvira Grandone | Zendy; Luciano Mariani | Zendy; P. Cordiali | Zendy; Aldo Di Carlo | Zendy; P Stentella | Zendy; A. Pachı́ | Zendy; Vito Michele Fazio | Zendy

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Lack of association between genetic variants in the mannose-binding lectin 2 (MBL2) gene and HPV infection

Author(s) -

Paola Parrella,

Davide Seripa,

Maria G. Matera,

Monica Rinaldi,

Emanuela Signori,

Carolina Gravina,

Antonietta Pia Gallo,

Maria Prencipe,

Elvira Grandone,

Luciano Mariani,

P. Cordiali,

Aldo Di Carlo,

P Stentella,

A. Pachı́,

Vito Michele Fazio

Publication year - 2007

Publication title -

european journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.825

H-Index - 111

eISSN - 1573-7284

pISSN - 0393-2990

DOI - 10.1007/s10654-007-9111-8

Subject(s) - mannan binding lectin , haplotype , genotype , medicine , allele , gene , immunology , lectin , hpv infection , virology , genetics , biology , cervical cancer , cancer

Genetic variants in the immunomodulatory gene mannose-binding lectin 2 (MBL2), were associated with risk, severity, and frequency of viral infections. In a case-control setting, we investigated the association of MBL2 functional polymorphisms with Human Papillomas Virus (HPV) infection. No differences between cases (HPV(+)) and controls (HPV(-)) were found in the distribution of each single genotypes or allele. Haplotype analysis did not show any difference between HPV+ and HPV(-) groups.

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