Paternal Age and Epilepsy in the Offspring | Zendy

Mogens Vestergaard | Zendy; Alissa Mork | Zendy; Kathrine Bang Madsen | Zendy; Jørn Olsen | Zendy

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Paternal Age and Epilepsy in the Offspring

Author(s) -

Mogens Vestergaard,

Alissa Mork,

Kathrine Bang Madsen,

Jørn Olsen

Publication year - 2005

Publication title -

european journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.825

H-Index - 111

eISSN - 1573-7284

pISSN - 0393-2990

DOI - 10.1007/s10654-005-4250-2

Subject(s) - medicine , offspring , epilepsy , epidemiology , public health , pediatrics , pregnancy , psychiatry , pathology , genetics , biology

Advanced paternal age is associated with a higher rate of de novo mutation in sperm cells and mental disorders in the offspring. In a population based cohort study of 96,654 children, we found that fathers aged 35 years or more were slightly more likely to have a child diagnosed with epilepsy compared to fathers aged 25-29 years. Our data suggest a modest paternal effect on the aetiology of epilepsy.

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