Open AccessEnteropathogenic Escherichia coli Infection Inhibits Intestinal Ascorbic Acid Uptake via Dysregulation of Its Transporter Expression
Author(s) -
Christopher W. Heskett,
Trevor Teafatiller,
Carly Hennessey,
Mélanie G. Gareau,
Jonathan S. Marchant,
Hamid M. Said,
Veedamali S. Subramanian
Publication year - 2020
Publication title -
digestive diseases and sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 124
eISSN - 1573-2568
pISSN - 0163-2116
DOI - 10.1007/s10620-020-06389-x
Subject(s) - enteropathogenic escherichia coli , western blot , biology , microbiology and biotechnology , ascorbic acid , transporter , jejunum , escherichia coli , biochemistry , gene , food science
Enteropathogenic Escherichia coli (EPEC) infection causes prolonged, watery diarrhea leading to morbidity and mortality. Although EPEC infection impacts nutrient transporter function and expression in intestinal epithelial cells, the effects of EPEC infection on intestinal absorption of ascorbic acid (AA) have not yet been investigated.