Open AccessValidation and Refinement of Noninvasive Methods to Assess Hepatic Fibrosis: Magnetic Resonance Elastography Versus Enhanced Liver Fibrosis Index
Author(s) -
Kenneth E. Sherman,
Enass A. Abdel-hameed,
Richard L. Ehman,
Susan D. Rouster,
Adriana Campa,
Sabrina Sales Martínez,
Yating Huang,
Gustavo G. Zarini,
Jacqueline Hernandez,
Colby Teeman,
Javier Tamargo,
Qingyun Liu,
Raúl N. Mandler,
Marianna K. Baum
Publication year - 2019
Publication title -
digestive diseases and sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 124
eISSN - 1573-2568
pISSN - 0163-2116
DOI - 10.1007/s10620-019-05815-z
Subject(s) - magnetic resonance elastography , medicine , receiver operating characteristic , fibrosis , cirrhosis , hepatology , gastroenterology , elastography , hepatitis c , area under the curve , hepatic fibrosis , cohort , liver fibrosis , magnetic resonance imaging , pathology , radiology , ultrasound
Noninvasive fibrosis markers are routinely used in patients with liver disease. Magnetic resonance elastography (MRE) is recognized as a highly accurate methodology, but a reliable blood test for fibrosis would be useful. We examined performance characteristics of the Enhanced Liver Fibrosis (ELF) Index compared to MRE in a cohort including those with HCV, HIV, and HCV/HIV.